Lille Europe (French: Gare de Lille-Europe) is a French railway station located in the French city of Lille, close to the Belgian border. The station is located on the northern line of the French high-speed railway. It mainly stops at the high-speed Eurostar and TGV, and also stops at the high-speed trains in the region.

There is a 500-meter passage between Lille Europe and Lille Flanders and connects to the Lille subway. Lille Europe and the adjacent Lillefrance station form the largest passenger railway transfer station in northern France.

Direct access to the site is Paris, Marne Valley (Paris Disneyland), Lyon, Valence (TGV station), Quimper, Rennes, Bordeaux, Le Mans, Avignon TGV station, Marseille, Nice, London, England, Brussels, Belgium, Amsterdam, Rotterdam, the Netherlands.