In the mid-nineteenth century Toledo was one of the first Spanish cities to receive rail service, being attached to the Madrid – Aranjuez line which was inaugurated by Isabella II on June 12 of 1858. The current station is in Neo-Mudéjar style, and was inaugurated on April 24 of 1919.

With several ups and downs in terms of technical equipment and services this is the line that served the city until the early twenty-first century: on July 2 of 2003 the last conventional train service between the two capitals ended and work began on the high-speed link, Madrid – Toledo, which entered service on November 16 of 2005, thanks to which travel time to Madrid has been reduced to just under 30 minutes.